Wires From The Bunker –

Traditional methods are serotonin inhibitors and antidepressants. They often have side effects such as sleep disturbance, weight gain or loss, migraines, sexual dysfunction, joint pain, gastrointestinal disorders, etc. In addition, many patients do not achieve complete remission. All this led to the fact that scientists began to look for alternative methods. The best cbd oil for anxiety is now available both in online and online stores.

Traditional anti-anxiety medications tend to target a type of serotonin receptor known as 5-HT1A. By acting on these receptors, the drug stimulates the production of serotonin. This leads to an improvement in mood and helps to temporarily reduce feelings of anxiety or fear. Research shows that CBD may work similarly, affecting not only 5-HT1A receptors but also several others that are responsible for regulating fear and anxiety. These receptors include the type 1 vanilloid receptor (TRPV1), the transient potential receptor, and the  CB1  and  CB2  receptors of the endocannabinoid system, the latter being much more abundant in the body than any other.

The Endocannabinoid system is formed in the early stages of evolution, it is present not only in mammals but also in other living beings, including molluscs. It is a universal signalling structure that controls many physiological functions. It includes endogenous cannabinoids,  CB1  and  CB2  receptors that interact with them, and enzymes that break them down after tasks are completed. CB1  receptors are concentrated predominantly in the brain and spinal cord and peripheral nervous system. Also, these receptors are found in almost all organs and systems.  Endocannabinoids are essentially intermediaries between the receptors of the system, they play a huge role in the self-regulation of the body. Structurally, endocannabinoids are lipids, and their production can be disrupted if a person does not get enough fatty acids from food.

Cannabidiol (CBD) is a substance similar in structure to endocannabinoids and also interacts with CB1  and  CB2  receptors. The mechanism of these interactions is still not fully understood. But many doctors around the world, based on the results of various studies, are already using CBD to treat diseases such as multiple sclerosis, epilepsy, neuropathic pain, movement disorders, injuries,  and others.

When it comes to anxiety, over a hundred studies have been conducted on the topic in the past few years, and 70% of them have shown positive results in reducing symptoms of anxiety and stress. The subjects began to feel calmer during public speaking and on stage, in closed or open spaces, the signs of social phobia decreased, and the feeling of discomfort when communicating with strangers disappeared. Experiments were carried out on both humans and animals.

Most of what we know about marijuana comes from a study of people who used it for chronic pain, but there is some compelling evidence that there are benefits to smoking the drug on a temporary basis. As an example of the effectiveness of cannabis, check out this article describing how someone treated her anxiety and depression by smoking one marijuana cigarette every day.

The research in the last few years on marijuana’s effectiveness against psychological disorders has been disappointing at best. The most thorough review to date, published in the Journal of Nervous and Mental Disease in 2007, did find that smoking pot reduced symptoms of anxiety, depression, and restlessness in participants with fibromyalgia. But the researchers concluded that the results were so mixed that more research would be needed before the benefits could be conclusively demonstrated.

Just as disappointing to me, because I was optimistic about marijuana as a treatment, is that in 2007 the National Institute on Drug Abuse responded to a Congressional request by confirming the meager scientific basis for medical marijuana in the United States. The National Institute’s spokeswoman told me at the time that “although marijuana is commonly used for medicinal purposes, the available evidence from well-designed scientific studies does not support the FDA’s current approval of marijuana for any use.”

delta 10 vs delta 8? All of that changed in 2010 with a pair of studies that showed that the cannabinoid Δ9-THC is effective at stopping the return of obsessive thoughts in people with obsessive-compulsive disorder (OCD) and enhancing the effectiveness of treatment in people with PTSD. And these studies also showed that the risk of developing PTSD-like symptoms after using the drug was similar to that of a placebo. What’s more, the amount of THC in the dosing regimen was significantly less than that in marijuana and similar to amounts used in the treatment of pain.

While a number of the participants with PTSD in those studies had severe anxiety disorders, most of the people with OCD were relatively free of anxieties, and it may be difficult to extend those findings to general populations of people with PTSD or OCD. The question of whether cannabis would be effective in treating other disorders is a different issue. In fact, a study of a cannabinoid commonly found in marijuana, known as cannabidiol, showed the substance to be highly effective at treating PTSD in people who had not experienced trauma.